Theta -defensins from Olive Baboon Leukocytes

Defensins are host defense peptides that play an important role in the innate immune response to pathogens. They are composed of the alpha, beta, and theta subclasses, which are produced by a variety of cells, including neutrophils, Paneth cells of the small intestine, and epithelial cells. theta-Defensins are macrocyclic antimicrobial peptides that were discovered in rhesus macaque leukocytes. They are produced by splicing of two nine-amino acid sequences derived from 76-amino acid precursors.