Acute Leukemias v Experimental Approaches and Management of Refractory Disease

This volume, the fifth in a series on acute leukemias, focuses particularly on recent basic research results and novel therapeutic approaches to the disease. Aspects of leukemia cell biology, including differentiation, the mechanisms of drug resistance, the pharmacology of cytostatic agents and the results of clinical trials in relapsed and refractory disease are covered by outstanding international experts in the respective fields. Future developments including new agents and new treatment options such as unrelated bone marrow transplantation, immunotargeting and gene therapy complete a state-of-the-art summery of current knowledge in experimental leukemia therapy.